Mechanism‑aware biosensing, built into living cells.

We engineer algal biosensors with multiplexed fluorescent reporters and ML/AI analysis to identify how chemicals act inside cells—reducing screening from weeks to hours.

  • High‑throughput
  • Mechanistic readouts
  • “Plate, perturb, observe” simplicity

Solutions

Agrochemical discovery

Rapidly characterize candidate compounds and prioritize leads with mechanism‑aware phenotypic profiles.

Water quality monitoring

Detect and characterize classes of environmental contaminants with sensitive cellular reporters—not just growth endpoints.

Industrial & environmental biotech

Screen complex mixtures and stressors to de‑risk processes and protect ecosystems.

Technology

Our assay builds the readout directly into biology. Engineered algal cells express multiplexed fluorescent reporters that map perturbations across pathways. Combine with high‑content imaging and ML to predict mechanisms of action.

  • Simple workflow: plate → perturb → observe
  • High‑content imaging with automated analysis
  • Interpretable ML/AI for MoA prediction
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Use cases

MoA triage in hit‑to‑lead

Rank hits by likely cellular targets using phenotypic similarity to reference compounds.

Mixture assessment

Characterize complex samples where traditional single‑endpoint assays fall short.

Environmental surveillance

Deploy to monitor waterways and industrial effluents for mechanism‑relevant stress signals.

About us

Built-N-Bioassays is a biotech startup dedicated to safer‑by‑design chemicals and resilient ecosystems. We blend cellular engineering, high‑content imaging, and machine learning to deliver actionable insight.

  • Backed by a Catalyst Grant
  • Advised by experts in nanotoxicology & environmental biotech
  • Committed to open, reproducible science
“Mechanism‑aware sensing is the cornerstone of next‑gen screening. We put it directly into the cell.”
— Built-N-Bioassays

Contact

Ready to see a demo or discuss a pilot? Send us a note.

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